Male Factors Crucial in Infertility: New Genetic Tech Offers Hope for Diagnosis

• A new Indian study reveals male factors play a major role in couple infertility, often overlooked.
• Traditional genetic tests (chromosome analysis, Y-chromosome testing) explain infertility in only a small fraction of men.
• Advanced DNA sequencing technologies (targeted sequencing, whole exome sequencing) significantly increase diagnostic yield.
• The study found that 1 in 8 to 1 in 5 infertile men may have an underlying genetic cause, often due to recessive inheritance.
• Genetic diagnosis helps in effective IVF planning, assessing risks for future children, and reducing emotional/financial burden.

Why It Matters: New genetic technology can accurately diagnose male infertility, offering clarity and guiding treatment for couples.