Doctors say advanced lipid tests like Apo B and Lp(a) can identify heart disease risk earlier than standard cholesterol checks. (Image: Pexels)
Lifestyle
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Moneycontrol22-12-2025, 10:30

Beyond LDL: AIIMS Doctor Reveals 2 Hidden Markers for Heart Attack Risk

  • AIIMS-trained Dr Priyanka Sehrawat highlights two under-recognized markers, Apo B and Lp(a), for more accurate heart attack prediction beyond just LDL cholesterol.
  • Apolipoprotein B (Apo B) indicates the number of harmful cholesterol-carrying particles (like LDL, VLDL) that can form plaque in arteries, even with normal LDL levels.
  • Apo B levels >90 mg/dL signal higher heart disease risk; >130 mg/dL indicates a high chance of heart attack, according to American Heart Association.
  • Serum Lipoprotein(a) [Lp(a)], similar to LDL but with an extra protein, is genetically determined and can cause plaque, inflammation, and blood clots.
  • Lp(a) levels >50 mg/dL are linked to higher heart disease risk (US National Library of Medicine); both markers require specific blood tests.

Why It Matters: Apo B and Lp(a) offer crucial insights into heart attack risk beyond traditional LDL cholesterol.

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