Eli Lilly's Oral Pill Maintains Weight Loss Post-Injections; FDA Approval Sought
Healthcare
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CNBC TV1818-12-2025, 18:39

Eli Lilly's Oral Pill Maintains Weight Loss Post-Injections; FDA Approval Sought

  • Eli Lilly's orforglipron pill helped patients maintain most weight loss after switching from injectable GLP-1 treatments like Zepbound and Wegovy.
  • The company submitted an application to the FDA for approval of the daily GLP-1 pill for obesity treatment, with priority review granted.
  • The late-stage trial showed the pill met its primary goal, demonstrating superior weight-loss maintenance compared to placebo.
  • It offers a needle-free maintenance option, addressing weight regain often seen after discontinuing injectable GLP-1 therapies.
  • The pill's safety profile was consistent with earlier studies, showing mild to moderate gastrointestinal issues as common side effects.

Why It Matters: Eli Lilly's new oral pill offers a promising needle-free option for long-term weight loss maintenance.

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