Oprah Winfrey, in her book Enough, shared her struggles with weight loss, adding how she got past the “shame of not being able to manage my weight.”
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Moneycontrol14-01-2026, 16:24

Oprah Winfrey Reveals GLP-1 Drug Side Effect & Her Simple Remedy

  • Oprah Winfrey openly discussed her use of GLP-1 drugs for weight loss and shared her experience in her new book ‘Enough’.
  • Unlike common gastrointestinal issues, Winfrey experienced constipation as a side effect from GLP-1 medications like Wegovy and Zepbound.
  • She found a personal remedy: consuming a gallon of water daily, primarily before 4 pm, combined with magnesium citrate.
  • Magnesium citrate helps draw water into the intestines, softening stool, while adequate water intake supports regular bowel movements.
  • In ‘Enough’, co-authored with Dr. Ania M. Jastreboff, Winfrey aims to destigmatize obesity, recognizing it as a chronic disease rather than a moral failing.

Why It Matters: Oprah Winfrey shares her personal battle with GLP-1 drug side effects, offering a simple hydration and magnesium remedy.

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