Losing weight in midlife helps metabolism — but new research suggests it may also temporarily stress the brain. Here’s what the study found and what it means for you. (Image: Pexels)
Lifestyle
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Moneycontrol30-12-2025, 09:03

Midlife Weight Loss Boosts Metabolism, But May Stress Brain: Study

  • Midlife weight loss improves metabolism, blood sugar, and reduces diabetes/heart risks.
  • A study on mice by Ben-Gurion University of the Negev found weight loss in older mice caused brain inflammation.
  • Inflammation in the hypothalamus, a brain region controlling appetite, was observed and lasted weeks.
  • Prolonged brain inflammation is linked to cognitive decline and diseases like Alzheimer's.
  • Dr Alon Zemer highlights weight loss benefits but urges more research on midlife brain response; consult doctors for a holistic approach.

Why It Matters: Midlife weight loss benefits metabolism but may cause temporary brain stress; holistic approach and more human research needed.

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