Harvard Uncovers Liver's 'Secret Pathway' to Control Obesity & Sugar!

• Harvard scientists discovered a liver pathway involving gut metabolites that regulate insulin sensitivity and fat storage, impacting obesity and sugar levels.
• Metabolites travel from the intestines via the hepatic portal vein to the liver, then to the heart, forming a 'gut-liver-heart triangle' that dictates metabolism.
• Unhealthy diets reduce beneficial metabolites; mice studies showed a high-fat diet decreased them from 111 to 48.
• A substance called Mesaconate, when applied to liver cells, improved insulin signaling, reduced fat accumulation, and boosted the Krebs cycle.
• This breakthrough offers hope for future 'probiotic' or 'metabolite therapy' to target the root cause of diabetes and obesity, though experts still emphasize lifestyle.

Why It Matters: Harvard's discovery of a liver pathway offers a new frontier for obesity and diabetes treatment.